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- PUBLICATIONS -

17.  McKnight, A. E.; Arora, R.; Pradhan, E.; Fujisato, Y. H.; Ajayi, A. J.; Lautens, M.; Zeng, T.;* Le, C.M.* BF3-Catalyzed Intramolecular Fluorocarbamoylation of Alkynes via Halide Recycling. J. Am. Chem. Soc. 2023145, 11012–11018. ChemRxIV pre-print: 10.26434/chemrxiv-2022-464nx-v2

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16.  McKnight, A. E.; Cadwallader, D.; Le, C.M.* Carbofluorination of π-Bonds and Related Reactions Involving Tandem C−C/C−F Bond Formation. Eur. J. Org. Chem. 2023, e202300017.

  • Featured in EurJOC's #NextGenOrgChem Collection

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15.  Cadwallader, D.; Tiburcio, T. R.; Cieszynski, G. A.; Le, C.M.* Synthesis of Carbamoyl Fluorides Using a Difluorophosgene Surrogate Derived from Difluorocarbene and Pyridine N-Oxides. J. Org. Chem. 2022, 87, 11457–11468.

  • 2023 JOC Outstanding Publication of the Year Award (Read the ACS Axial Interview with Christine)

  • Selected as an ACS Editors' Choice Article

  • Among the most read recently published articles in JOC for 2022

  • Highlighted in Organic Chemistry Portal

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14.  Le, C. M.* A hot take on glucose. Nat. Chem. 2022, 14, 476.

  • Invited contribution to Nature Chemistry's In Your Element column

 

13.  Le, C. M.* Direct installation of boron groups offers boost to medicinal chemistry. Nature 2021, 595, 652–653.

  • Invited contribution to Nature News & Views column

12.  Ackerman-Biegasiewicz, L. K. G.; Arias-Rotondo, D. M.; Biegasiewicz, K. F.; Elaqua, E.;* Golder, M. R.; Kayser, L. V.; Lamb, J. R.; Le, C. M.; Romero, N. A.; Wilkerson-Hill, S. M.; Williams, D. A. Organic Chemistry: A Retrosynthetic Approach to a Diverse Field. ACS Cent. Sci. 20206, 1845–1850.

Prior to independent career

11.   Chapman, S. J.; Swords, W. B.; Le, C. M.; Guzei, I. A.; Toste, F. D.; Yoon, T. P.* Cooperative Stereoinduction in Asymmetric Photocatalysis. J. Am. Chem. Soc. 2022144, 4206–4213.

10.   Le, C. M.; Morra, B.* Retrosynthetic Graphic Organizers and Molecule of the Week Activities in Organic  Chemistry Tutorials. J. Chem. Educ. 2019, 96, 1640–1645.

9.    von Delius, M.;* Le, C. M.; Ellinger, B.; Kuzikov, M.; Gul, S.;* Dong, V. M.* Synthesis and Biological Activity of Octaketides from the Cytosporone Family. Isr. J. Chem. 2017, 57, 975–981.

8.    Sperger, T.; Le, C. M.; Lautens, M.;* Schoenebeck, F.* Mechanistic Insights on the Pd-Catalyzed Addition of C–X Bonds across Alkynes – A Combined Experimental and Computational Study. Chem. Sci. 2017, 8, 2914–2922.

7.    Le, C. M.; Sperger, T.; Fu, R.; Hou, X.; Lim, Y. H.; Schoenebeck, F.;* Lautens, M.* Stereoselective Synthesis of Methylene Oxindoles via Palladium(II)-Catalyzed Intramolecular Cross-Coupling of Carbamoyl Chlorides.         J. Am. Chem. Soc. 2016, 138, 14441–14448.

6.    Le, C. M.; Hou, X.; Sperger, T.; Schoenebeck, F.;* Lautens, M.* An Exclusively trans-Selective Chlorocarbamoylation of Alkynes Enabled by a Palladium/phosphaadamantane Catalyst. Angew. Chem. Int. Ed. 2015, 54, 15897–15900.

5.    Le, C. M.; Menzies, P. J. C.; Petrone, D. A.; Lautens, M.* Synergistic Steric Effects in the Development of a Palladium-Catalyzed Alkyne Carbohalogenation: Stereodivergent Synthesis of Vinyl Halides. Angew. Chem. Int. Ed. 2015, 54, 254–257.

4.    Petrone, D. A.; Le, C. M.; Newman, S. G.; Lautens, M.* Pd(0)-Catalyzed Carboiodination: Early Developments and Recent Advances. In New Trends in Cross-Coupling: Theory and Applications; 1st ed. Colacot, T. J. Ed. RCS Publishing: 2014; pp 276–321.

3.    Zhang, L.; Le, C. M.; Lautens, M.* The Use of Silyl Ketene Acetals and Enol Ethers in the Catalytic Enantioselective Alkylative Ring Opening of Oxa/Aza Bicyclic Alkenes. Angew. Chem. Int. Ed. 2014, 53, 5951–5954.

2.    von Delius, M.; Le, C. M.; Dong, V. M.* Rhodium-Phosphoramidite Catalyzed Alkene Hydroacylation: Mechanism and Octaketide Natural Product Synthesis. J. Am. Chem. Soc. 2012, 134, 15022–15032.

1.    Martin, C. D.; Le, C. M.; Ragogna, P. J.* Remarkably Stable Chalcogen(II) Dications.  J. Am. Chem. Soc. 2009, 131, 15126–15127.

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